Innate Immune Response Produces ‘Phenomenal’ Breast Cancer Control

  Watch the Video Here: https://www.medscape.com/viewarticle/937996 Hi. It’s Dr Kathy Miller with Indiana University. There is another really important study from the science weekend at ESMO that I want to make sure you see because I fear it might be overlooked. It’s the PARADIGM analysis. This was a correlative analysis, not an individual clinical trial. The authors were interested in looking at the potential impact of our innate immune response, our body’s ability to recognize a triple-negative tumor and potentially to control it on outcome. To avoid the potential confounders of the effects of our treatment, the investigators looked at women who did not receive systemic therapy. This is a really unique cohort. All of these women were younger than age 40, had triple-negative or low ER–expressing tumors (ER and PR less than 10%), 50% of them were T1Cs (tumors